By Shamim Tejani PharmD, Cynthia A. Sanoski BS PharmD FCCP BCPS
Davis's Pocket scientific Drug Reference is a short source for the main everyday medications in medical perform. The monographs are designed to spotlight pertinent details; in particular, every one monograph incorporates a drug's known identify, model identify, therapeuticindication, pharmacologic type, being pregnant classification, contraindications, antagonistic drug reactions, drug interactions, dose, availability, and tracking parameters.
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Extra info for Davis's Pocket Clinical Drug Reference
MAC—5 mg/kg daily (max: 250 mg/day) or 20 mg/kg (max: 1200 mg/dose) once weekly (alone or with rifabutin); IV: PO: Adults: CAP—500 mg IV daily for ≥ 2 days, then 500 mg PO daily for total of 7–10 days; PID—500 mg IV daily for 1–2 days, then 250 mg PO daily for total of 7 days; Ophth: Adults and Peds: ≥1 yr 1 drop bid × 2 days, then 1 drop daily × 5 days; Availability (G): Tabs: 250, 500, 600 mg; Oral susp: 100 mg/5 ml, 200 mg/5 ml, 1 g/pkt; ER oral susp (Zmax): 2 g; Inject: 500 mg; Ophth soln: 1%; Monitor: HR, BP, temp, sputum, U/A, CBC, LFTs; Notes: ER susp is not interchangeable with other susp.
IT delivered by implantable IT pump. → B susp (Zmax). Acute bacterial exacerbations of COPD—500 mg on Day 1, then 250 mg daily × 4 days or 500 mg daily × 3 days. Acute bacterial sinusitis—500 mg daily × 3 days or single 2-g dose of ER susp (Zmax). Chancroid/nongonococcal urethritis or cervicitis—1-g single dose. Gonococcal urethritis/cervicitis—2-g single dose. 5 g), or 10 mg/kg daily × 3 days (max: 500 mg/day), or 10 mg/kg (max: 500 mg/ day) on Day 1, then 5 mg/kg (max: 250 mg/day) daily × 4 days.
IE prophylaxis—2 g 30–60 min before procedure; PO: Peds: >3 mo 20–50 mg/kg/day divided q 8 hr or 25–50 mg/kg/day divided q 12 hr; Acute OM due to highly resistant S. pneumo—80–90 mg/kg/day divided q 12 hr; PO: Infants: ≤3 mo and Neonates 20–30 mg/kg/day divided q 12 hr. IE prophylaxis—50 mg/kg 1 hr before procedure (max: 2 g/dose); Renal Impairment: PO: Adults: dose if CrCl ≤30 ml/min; Availability (G): Chew tabs: 125, 200, 250, 400 mg; Tabs: 500, 875 mg; Caps: 250, 500 mg; Oral drops: 50 mg/ml; Oral susp: 125 mg/ 5 ml, 200 mg/5 ml, 250 mg/5 ml, 400 mg/5 ml; Monitor: HR, BP, → A → 12 amlodipine → CAPITALS indicates life-threatening; underlines indicate most frequent amphetamine mixtures 13 temp, sputum, U/A, CBC, LFTs, BUN/SCr; Notes: Use with caution in patients with beta-lactam allergy (do not use if history of anaphylaxis or hives).