By Alan S. Curry
This choice of 9 essays by way of prime professionals considers the appliance of the main lately constructed analytical strategies and kit to specific poisons and medicine. It describes using HPLC, fluorescence research, and radioimmunoassays in toxicology and exhibits equipment particular to forensic drugs.
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Extra info for Analytical Methods in Human Toxicology: Part 2
And Van Hal, H. J. M. (1981). In Reid, E. ), Trace Organic Sample Handling , Vol. 10. Methodological Surveys in Biochemistry. Ellis Horwood , Chichester, 214-17 . Petterson, c.. and Schill, G. (1981) . J. Chromatogr. 204 , 179-83. Proske, M. , and Huebinger, E. (1982). J. Chromatogr. 240 , 95 . , Harrison, A. D. , and Leppard, J. P. (1981). In Reid, E. ), Trace Organic Sample Handling, Vol. 10. Methodological Surveys in Biochemistry. Ellis Horwood, Chichester, 366-8. , Huen, J. , and Frei , R.
The wavelength (or frequency, as it is more commonly expressed) at which absorption occurs is characteristic of a particular bond. Infrared is therefore particularly useful as a qualitative tool. r. is probably the most powerful tool for the identification of organic compounds even though relatively large amounts of sample are required. r, allows greater sensitivity by repeatedly scanning the spectrum such that data is arranged and noise levels (which are random) are lowered with respect to the sample signal.
This enables the laboratory manager to compare the performance of his own laboratory with that of others carrying out the same assay. 6 CONCLUSIONS There is no single analytical technique which is universally applicable. Careful selection of technique has therefore to be made for each new assay situation. Although very few novel techniques are emerging, major advances in methodology are regularly being achieved by adaptions of existing systems. The impact made by HPLC in the last few years is a particular illustration of this process.